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BCI Pharma Enters into Strategic Partnership with Mithra to Identify Novel Therapy for Endometriosis and Cancer in Women

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BCI Pharma Enters into Strategic Partnership with Mithra to Identify Novel Therapy for Endometriosis and Cancer in Women | Pharmtech Focus

BCI Pharma, owner of a proprietary kinase technology platform, and Mithra, a global independent pharmaceutical group, today announce that they have entered into a collaboration and license option agreement to identify new kinase inhibitors for treating endometriosis, cancer in women and other diseases. BCI Pharma will identify preclinical candidates and Mithra will carry out the clinical development.

Mithra acquired a purchase option on the rights to two development programs in innovative CSF1R kinase inhibitors, led by BCI Pharma. Under the terms of the contract, Mithra has the possibility to buy the rights to a development program on inhibitors with an undisclosed upfront payment upon execution of an option linked to the initial results. Other milestones payments are planned.

“We are very pleased to sign this partnership with Mithra. We see it as an important validation of the progress made by BCI Pharma since its founding in 2013. Mithra is a major pharmaceutical company with solid experience in women’s health; we will benefit from this collaboration in multiple ways. We are also confident that the partnership will prove valuable to Mithra and provide new avenues for the treatment of endometriosis and cancer in women,” said Dominique Surleraux, CEO of BCI Pharma.

This partnership will combine BCI’s research with Mithra’s clinical development and marketing expertise. The objective is to deliver new therapeutic options using BCI’s kinase technology platform and to create value for both companies and their investors. Currently in the preclinical stage, BCI Pharma anticipates starting clinical development in 2023, with marketing authorizations expected for 2031.

Leon Van Rompay, CEO of Mithra Women’s Health, added: “We are very pleased to collaborate with BCI Pharma on this innovative development opportunity in a fast-growing market. It will allow us to diversify our pipeline in women’s health and beyond. In addition to our innovative Estetrol-based product portfolio, this partnership on a very promising inhibitor should provide the many women living with these health conditions with new treatment options for highly invasive pathologies such as endometriosis and breast cancer.”

Didier Malherbe, chairman of the board at BCI Pharma, welcomes this collaboration: “I am delighted with this partnership between two Walloon biotechnology companies. This demonstrates the ability of the biotech sector to create value in a very dynamic R&D environment, supported by the Belgian federal government and the Walloon administration.”

The inhibitor market is valued at some $40.3bn (€35.6bn), according to Mithra.

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